- 何涛;李非;古槿;李瑞强;李飞;
In recent years, much effort has been made in identifying microRNA (miRNA) genes from mammals, insects, worms, plants, and viruses. Continuing the search for more miRNA genes is still important but diffi-cult. This paper presents a computational strategy based on comparative genomics analysis. The algorithm was used to scan four invertebrate genomes, Drosophila melangoster, Bombyx mori, Apis mellifera, and Anopheles gambiae, which are either model organisms or medically/economically important insects. 99 new miRNA genes were predicted from the four insect species which can be grouped into 17 miRNA gene fami-lies, of which 10 of the miRNA families are insect-specific. Sequence similarity analysis showed that 16 of the newly predicted insect miRNAs belong to the K-box, GY-box, and Brd-box miRNA families which are impor-tant participators in Notch-related pathways. To test the validity of the algorithm, 39 predicted insect miRNA genes from D. melangoster and A. mellifera were selected for further biological validation. 34 (87%) pre-dicted miRNA genes’ transcripts were successfully detected by reverse transcription-polymerase chain reac-tion experiments. Thus, this strategy can be used to efficiently screen for miRNA genes conserved cross species.
2008年04期 425-432页 [查看摘要][在线阅读][下载 584K] [下载次数：135 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 应剑;董晓楠;陈应华;
A multi-epitope-vaccine MEVABC consisting of two linear neutralizing determinants (BC1: aa693-716; A6: aa844-865) located on antigenic unit B/C and unit A of glycoprotein E2 was prepared to evaluate whether a combination strategy is effective in the design of peptide vaccines. After immunization, pig sera collected every one to two weeks were evaluated by enzyme linked immunosorbent assay. C-strain- induced anti-sera and hyper-immune sera cannot recognize overlapping peptides that cover the E2 N-terminus, while MEVABC is able to elicit high levels of peptide-specific antibody response. When compared with previously studied peptide vaccines PV-BC1 and PV-A6, the same dose of either component in the MEVABC increases the BC1- or A6-specific antibodies (to 1/3-1/2 of the levels of the separate vaccines). However, the synergy between the antibodies may make MEVABC much more potent. Moreover, anti-C-strain immunity pre-existing in pigs does not disturb the sequent MEVABC vaccination. Thus, MEVABC can be ad-ministrated to pigs which already possess anti-classical swine fever virus immunity. MEVABC is a promising candidate marker vaccine.
2008年04期 433-438页 [查看摘要][在线阅读][下载 552K] [下载次数：39 ] |[网刊下载次数：0 ] |[引用频次：1 ] |[阅读次数：0 ] - 王雪;范为民;谢莉萍;张荣庆;
Plasma membrane calcium ATPase (PMCA) plays a critical role in transporting Ca2+ out of the cy-tosol across the plasma membrane which is essential both in keeping intracellular Ca2+ homeostasis and in biomineralization. In this paper we cloned and localized a gene encoding PMCA from the pearl oyster Pinc-tada fucata. This PMCA shares similarity with other published PMCAs within the functional domains. Reverse transcription-polymerase chain reaction analysis shows that it is expressed ubiquitously. Furthermore, in situ hybridization reveals that it is expressed in the inner epithelial cells of the outer fold and in the outer epithelial cells of the middle fold, as well as the edge near the shell, which suggests that PMCA may be involved in calcified layer formation. The identification and characterization of oyster PMCA can help to further under-stand the structural and functional properties of molluscan PMCA, as well as the mechanism of maintaining Ca2+ homeostasis and the mechanism of mineralization in pearl oyster.
2008年04期 439-446页 [查看摘要][在线阅读][下载 227K] [下载次数：52 ] |[网刊下载次数：0 ] |[引用频次：2 ] |[阅读次数：0 ] - 陈松;朱文婷;周全;陈国强;
The cytotoxicity and apoptotic effect of phytoceramide IV (N-palmitoyl-phytospingosine) were in-vestigated by preparaing the ceramide containing liposomes using cholesteryl hemisuccinate (CHEMS) and methoxypolyethylene glycol (2000) cholesteryl succinate (PEGCHS). The ceramide-containing liposomes prepared using ultrasonication contained CHEMS and the phytoceramide IV at a molar ratio of 1:1. Gel chromatography and high performance liquid chromatography equipped with an evaporative light-scattering detection (HPLC-ELSD) were used to analyze the liposomes. The results show that the ceramide entrapment efficiency is over 90% and the molar ratio of phytoceramide IV to CHEMS is 1:1.4. The ratio of ceramide to CHEMS as well as the ultrasonication duration affects the liposome properties. The phytoceramide IV en-capsulated in the liposomes reduces the cellular activity of the murine mastocytoma cell line P815 in a dose-dependent manner and the reduction of cellular activity is due to cell apoptosis. 4, 6-diamidino- 2-phenylindole dihydrochloride (DAPI) staining further supports this result. The encapsulation of highly hy-drophobic ceramides into liposomal formulations could become a potential candidate for enhanced apoptosis.
2008年04期 447-453页 [查看摘要][在线阅读][下载 209K] [下载次数：38 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 朱江;何华伟;李森;
The effect of dextran on the conformation (or secondary structure) and thermal stability of creatine kinase (CK) was studied using the far-ultraviolet (UV) circular dichroism (CD) spectra. The results showed that lower concentrations of dextran (less than 60 g/L) induced formation of the secondary CK structures. However, the secondary structure content of CK decreased when the dextran concentrations exceeded 60 g/L. Thermally induced transition curves were measured for CK in the presence of different concentrations of dextran by far-UV CD. The thermal transition curves were fitted to a two-state model by a nonlinear, least-squares method to obtain the transition temperature of the unfolding transition. An increase in the tran-sition temperature was observed with the increase of the dextran concentration. These observations qualita-tively accord with predictions of a previously proposed model for the effect of intermolecular excluded volume (macromolecular crowding) on protein stability and conformation. These findings imply that the effects of macromolecular crowding can have an important influence on our understanding of how protein folding oc-curs in vivo.
2008年04期 454-459页 [查看摘要][在线阅读][下载 349K] [下载次数：51 ] |[网刊下载次数：0 ] |[引用频次：2 ] |[阅读次数：0 ] - 向兰;邢东明;雷帆;王伟;徐丽珍;聂磊;杜力军;
Ellagic acid (EA) has aroused great interest worldwide owing to its antioxidant, anti-inflammatory, and anticarcinogenetic properties. The EA content in pomegranate leaf was measured in this study using high performance liquid chromatography to investigate the effects of season, variety, and processing method on the EA level. The results show that the EA content in 11 varieties of pomegranate from the Zaozhuang region in China range from 1.30 mg · g–1 to 6.46 mg · g–1 of dry weight in five consecutive seasons from June to October. An analysis of variance (ANOVA) shows that the EA content is significantly dependent on the season (p<0.05). The EA content increases significantly during the growing season to the highest level in September and October. The effect of the leaf variety on the EA content is less significant than the season. The processing methods have different effects on the EA content. Soaking for 24 hours slightly increases the EA content (p<0.05). Heating at 80 ℃ or 100 ℃ for 1 h after soaking has little influence on the EA content, while slow-fired cooking at high temperature significantly elevates the EA content (p<0.05). To improve qual-ity and stability, several parameters such as leaf collection time, slow-fired cooking, and cooking time should be strictly controlled during the processing of pomegranate leaf tea and its extract.
2008年04期 460-465页 [查看摘要][在线阅读][下载 185K] [下载次数：69 ] |[网刊下载次数：0 ] |[引用频次：13 ] |[阅读次数：0 ] - 范为民;胡轶霖;李长忠;谢莉萍;张荣庆;
Calreticulin is a unique calcium-binding protein with multiple functions mostly located in the sar-coplasmic/endoplasmic reticulum. A large amount of calcium is absorbed from the medium and transported to mineralization sites during biomineralization in pearl oyster. This paper describes the cloning of the full-length cDNA of calreticulin from Pinctada fucata, namely PCRT. PCRT encodes a deduced 414-amino acid protein, which includes a predicted 17- amino acid signal peptide and an endoplasmic reticulum retrieval sequence HDEL. The protein shows 63%-76% sequence identity and shares some common characteristics with calreticulins from other species. Semi-quantitative RT-PCR indicates that PCRT is ubiquitously ex-pressed in all tissues tested with the highest expression in the hemolymph and the mantle. In situ hybridiza-tion analysis of PCRT in the mantle showed strong signals in the inner fold, the inner side of middle fold, and the inner side of outer fold of the mantle epithelium. All these results suggest PCRT might be involved in Ca2+ transport and storage during oyster biomineralization.
2008年04期 466-473页 [查看摘要][在线阅读][下载 300K] [下载次数：79 ] |[网刊下载次数：0 ] |[引用频次：4 ] |[阅读次数：0 ] - 胡珺;闫晓玲;王伟;吴昊;花雷;杜力军;
Antioxidant activities of the 95% ethanol extract from Caesalpinia sappan heartwood (ECS), pro-tosappanin A, protosappanin B, and brazilein were studied in vitro. The inhibition of the formation of malondialdehyde (MDA) and the scavenging of superoxide anions, hydrogen peroxide, and hydroxyl radicals were assayed. The experimental results show that all four substances had antioxidant activity in vitro but their capabilities differed for the different indicators. ECS, protosappanin A, and protosappanin B show more inhi-bition of MDA and scavenging of hydrogen peroxide, while brazilein shows more scavenging of hydroxyl radicals. All the samples show little scavenging of superoxide anions.
2008年04期 474-479页 [查看摘要][在线阅读][下载 291K] [下载次数：111 ] |[网刊下载次数：0 ] |[引用频次：15 ] |[阅读次数：0 ] -
<正>"Todai Week at Tsinghua", a major communication event between Tsinghua University and the University of Tokyo (Todai), started May 19. The University of Tokyo is the first partner institution in Asia with which Tsinghua has
2008年04期 479页 [查看摘要][在线阅读][下载 68K] [下载次数：9 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 邹和昌;蔡光圻;蔡文;李海龙;顾益;朴龙斗;孟凡国;
This study investigated the extraction of 5’-phosphodiesterase from malt root and the degradation of nucleic acids by this enzyme. The extraction used grade precipitation with ammonium sulfate and enzy-matic hydrolysis. Samples were assayed using the modified Bradford method and high performance liquid chromatography. The results show that 5’-phosphodiesterase is isolated by grade precipitation with 30% and 80% saturation of ammonium sulfate and can be utilized to degrade deoxyribonucleic acid. The hydrolysate has four kinds of deoxynucleotides: 5’-dCMP, 5’-dTMP, 5’-dAMP, and 5’-dGMP. The optimum reaction tem-perature is 70℃, and the optimum pH is 5.5-6.0 for the reaction. The percentage of deoxynucleotides indi-cated by the China Pharmacopoeia (2000 edition) in the product is over 70%. The extraction of 5’-phosphodiesterase from malt root is shown to be possible and economical. Products from the enzymatic hydrolysate of DNA meet the pharmacopoeia.
2008年04期 480-484页 [查看摘要][在线阅读][下载 354K] [下载次数：45 ] |[网刊下载次数：0 ] |[引用频次：5 ] |[阅读次数：0 ] -
<正>Tsinghua University recently announced the reestablishment of its Department of Psychology (PSYC) under the School of Humanities and Social Sciences.
2008年04期 484页 [查看摘要][在线阅读][下载 65K] [下载次数：20 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 兰嘉琦;炎彬;赵玉男;王道义;胡珺;邢东明;杜力军;
Previous studies have shown that mice experiencing cerebral ischemia reperfusion (CIR) and stress can serve as a model of post stroke depression (PSD). The present study verified the acute antide-pressant effects of radix puerariae extract (PE) on PSD mice through behavior and gene expression ex-periments. CIR was found to reduce the sucrose consumption and tyrosine hydroxylase (TH) gene expres-sion. PE administration after CIR surgery was observed to significantly enhance the mRNA expression of TH in the hippocampus compared with the PSD group on Day 0 and Day 3 postsurgery. These findings in-dicate that PE contributes to the amelioration of behavior response in PSD mice, which is closely related with the protective effects of catecholamine synthesize against CIR brain damage.
2008年04期 485-491页 [查看摘要][在线阅读][下载 289K] [下载次数：68 ] |[网刊下载次数：0 ] |[引用频次：6 ] |[阅读次数：0 ] - 黄子纹;崔婷;刘晶;庄源;孟庆航;陶李涛;李珍;
Adiponectin is one of the hormones secreted exclusively by the adipose tissue with anti-diabetic, anti-inflammatory, anti-atherogenic, anti-atherosclerotic, and insulin-sensitizing effects. Adiponectin has structural features including a signal peptide at the N terminus, a short variable region, a collagenous domain, and a C-terminal globular domain homologous to C1q. The family of proteins containing this globular domain is called the C1q/tumor necrosis factor-α-related proteins (CTRP). Among all the CTRPs characterized so far, the CTRP9 protein has the highest homology to adiponectin. However, little is known about the functions of CTRP9. This study examines the tissue expression of CTRP9 as well as the ex-pression of CTRP9 during mouse development and 3T3-L1 preadipocyte differentiation. The effects of LPS, TNFα, and starvation on the expression of CTRP9 were also investigated. CTRP9 mRNA is shown to be expressed in a variety of tissues including the adipose tissues. The expression profile of CTRP9 dif-fers from that of adiponectin, implying that they are functionally diverse although structurally homologous.
2008年04期 492-499页 [查看摘要][在线阅读][下载 381K] [下载次数：189 ] |[网刊下载次数：0 ] |[引用频次：14 ] |[阅读次数：0 ] <正>During Berkeley Week at Tsinghua, University of California at Berkeley Executive Vice Chancellor and Provost George Breslauer granted an interview to the Tsinghua News Center in which he shared his ideas about education,
2008年04期 499页 [查看摘要][在线阅读][下载 93K] [下载次数：21 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 郑秋豫;张俊祥;
This study presents evidence from analyses of the acoustic parameters of fluent continuous speech to show that within-paragraph prosodic phrase boundaries are related more to contrasts of neighborhood prosodic states rather than between-phrase pause durations; prosodic states receive more constraints from higher level discourse information. By revising a modular acoustic model by Tseng’s hier-archical prosodic phrase grouping framework and examining the much varied prosodic phrase (PPh) boundary B3 within speech paragraph, we show that statistical accounts of layered contributions reveal dis-tinct contrasts between boundary immediate duration and intensity patterns irrespective of pause duration. Contrasts of F0 contour patterns were also observed in these locations. Evidence was also obtained to illus-trate how PPh boundary states are specified more by higher level discourse information than by lower level prosodic word construction. These combined results suggest that contrastive neighboring prosodic states are more significant cues to PPh boundaries than boundary pause duration. The results also help explain why in fluent speech between-phrase pause durations vary greatly, and can be applied to automatic speech segmentation.
2008年04期 500-509页 [查看摘要][在线阅读][下载 1580K] [下载次数：114 ] |[网刊下载次数：0 ] |[引用频次：5 ] |[阅读次数：0 ] - 双志伟;Raimo Bakis;秦勇;
This paper proposes a novel voice conversion method by frequency warping. The frequency warp-ing function is generated based on mapping formants of the source speaker and the target speaker. In addi-tion to frequency warping, fundamental frequency adjustment, spectral envelope equalization, breathiness addition, and duration modification are also used to improve the similarity to the target speaker. The pro-posed voice conversion method needs only a very small amount of training data for generating the warping function, thereby greatly facilitating its application. Systems based on the proposed method were used for the 2007 TC-STAR intra-lingual voice conversion evaluation for English and Spanish and a cross-lingual voice conversion evaluation for Spanish. The evaluation results show that the proposed method can achieve a much better quality of converted speech than other methods as well as a good balance between quality and similarity. The IBM1 system was ranked No. 1 for English evaluation and No. 2 for Spanish evaluation. Evaluation results also show that the proposed method is a convenient and competitive method for cross-lingual voice conversion tasks.
2008年04期 510-514页 [查看摘要][在线阅读][下载 136K] [下载次数：41 ] |[网刊下载次数：0 ] |[引用频次：2 ] |[阅读次数：0 ] - 张巍;凌震华;胡国平;王仁华;
The employment of non-uniform processes assists greatly in the corpus-based text-to-speech (TTS) system to synthesize natural speech. However, tailoring a TTS voice font, or pruning redundant syn-thesis instances, usually results in loss of non-uniform synthesis instances. In order to solve this problem, we propose the concept of virtual non-uniform instances. According to this concept and the synthesis fre-quency of each instance, the algorithm named StaRp-VPA is constructed to make up for the loss of non-uniform instances. In experimental testing, the naturalness scored by the mean opinion score (MOS) re-mains almost unchanged when less than 50% instances are pruned, and the MOS is only slightly degraded for reduction rates above 50%. The test results show that the algorithm StaRp-VPA is effective.
2008年04期 515-521页 [查看摘要][在线阅读][下载 263K] [下载次数：28 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 赵剑;董远;赵贤宇;杨浩;陆亮;王海拉;
For text-independent speaker verification, the Gaussian mixture model (GMM) using a universal background model strategy and the GMM using support vector machines are the two most commonly used methodologies. Recently, a new SVM-based speaker verification method using GMM super vectors has been proposed. This paper describes the construction of a new speaker verification system and investigates the use of nuisance attribute projection and test normalization to further enhance performance. Experiments were conducted on the core test of the 2006 NIST speaker recognition evaluation corpus. The experimental results indicate that an SVM-based speaker verification system using GMM super vectors can achieve ap-pealing performance. With the use of nuisance attribute projection and test normalization, the system per-formance can be significantly improved, with improvements in the equal error rate from 7.78% to 4.92% and detection cost function from 0.0376 to 0.0251.
2008年04期 522-527页 [查看摘要][在线阅读][下载 321K] [下载次数：65 ] |[网刊下载次数：0 ] |[引用频次：2 ] |[阅读次数：0 ] - 廖元甫;庄智显;杨智合;
Unseen handset mismatch is the major source of performance degradation in speaker identifica-tion in telecommunication environments. To alleviate the problem, a maximum likelihood a priori knowledge interpolation (ML-AKI)-based handset mismatch compensation approach is proposed. It first collects a set of handset characteristics of seen handsets to use as the a priori knowledge for representing the space of handsets. During evaluation the characteristics of an unknown test handset are optimally estimated by in-terpolation from the set of the a priori knowledge. Experimental results on the HTIMIT database show that the ML-AKI method can improve the average speaker identification rate from 60.0% to 74.6% as compared with conventional maximum a posteriori-adapted Gaussian mixture models. The proposed ML-AKI method is a promising method for robust speaker identification.
2008年04期 528-532页 [查看摘要][在线阅读][下载 264K] [下载次数：30 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 曹文;张劲松;
To investigate how a low tone (tone-3, T3) syllable in Chinese can be perceived to be focal ac-cented or not, a total of 156 sentences containing tone-3 words were synthesized and used as stimuli in a perceptual study. The sentences differed in the falling value between the two high pitches, and in the dura-tion and phonation types of the T3 syllables. Thirty-nine subjects were asked to judge where the focus or accent was for each sentence. The results show that at least three degrees of pitch drop are involved in the focus recognition: a big sized drop of about 10 semitones; a middle sized drop of about 6 semitones; a small sized drop of about 2 semitones. The results suggest that the three sizes of pitch drop have different indica-tions in Chinese intonation, depending on both the tone and the tone combination. In perception, there are various ways to realize tone-3 focus in the Tx-T3-Ty sentences series, but in production or for text-to-speech synthesis, the rule simply is making a middle sized pitch drop with a long and creaky T3 syllable. Similarly, to focus on the low tone syllable in the T3-Tx-Ty sentences, a creaky T3 syllable is essential. However, a long T3 syllable is a strong determinant for a low tone focus in the Tx-Ty-T3 sentences.
2008年04期 533-539页 [查看摘要][在线阅读][下载 704K] [下载次数：206 ] |[网刊下载次数：0 ] |[引用频次：5 ] |[阅读次数：0 ] - Tohru Shimizu;Yutaka Ashikari;Eiichiro Sumita;张劲松;Satoshi Nakamura;
This paper describes the latest version of the Chinese-Japanese-English handheld speech-to-speech translation system developed by NICT/ATR, which is now ready to be deployed for travelers. With the entire speech-to-speech translation function being implemented into one terminal, it realizes real-time, location-free speech-to-speech translation. A new noise-suppression technique notably improves the speech recognition performance. Corpus-based approaches of speech recognition, machine translation, and speech synthesis enable coverage of a wide variety of topics and portability to other languages. Test results show that the character accuracy of speech recognition is 82%-94% for Chinese speech, with a bilingual evaluation understudy score of machine translation is 0.55-0.74 for Chinese-Japanese and Chinese-English.
2008年04期 540-544页 [查看摘要][在线阅读][下载 304K] [下载次数：125 ] |[网刊下载次数：0 ] |[引用频次：12 ] |[阅读次数：0 ] - 张劲松;Takatoshi Jitsuhiro;Hirofumi Yamamoto;胡新辉;Satoshi Nakamura;
This paper introduces several important features of the Chinese large vocabulary continuous speech recognition system in the NICT/ATR multi-lingual speech-to-speech translation system. The features include: (1) a flexible way to derive an information rich phoneme set based on mutual information between a text corpus and its phoneme set; (2) a hidden Markov network acoustic model and a successive state split-ting algorithm to generate its model topology based on a minimum description length criterion; and (3) ad-vanced language modeling using multi-class composite N-grams. These features allow a recognition per-formance of 90% character accuracy in tourism related dialogue with a real time response speed.
2008年04期 545-552页 [查看摘要][在线阅读][下载 618K] [下载次数：130 ] |[网刊下载次数：0 ] |[引用频次：3 ] |[阅读次数：0 ] - 吴筱如;杨瑛;
Most change-point models assume that the response is continuous or cross sectional binary. However, in many public health problems, the data is longitudinal binary. There are few studies of change-point problems for longitudinal outcomes. This paper describes a flexible change-point model which includes random-effects and takes into account the difference between various individuals in longitudinal binary data. A transition function is used to make the linear-linear logistic model differentiable at the change-point. The location of the change-point is estimated using the maximum likelihood method. Adjust-ment of the transition parameter from zero to one controls the sharpness of the transition. The performance of this estimation procedure is illustrated with simulations using SAS/proc nlmixed and a detailed analysis of data relating hormone levels and ovary functions based on data from the Obstetrics and Gynecology Hospi-tal, Medical Center of Fudan University.
2008年04期 553-559页 [查看摘要][在线阅读][下载 379K] [下载次数：51 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ] - 陈丽;陈秀卿;
This paper studies the existence, semiclassical limit, and long-time behavior of weak solutions to the unipolar isentropic quantum drift-diffusion model, a fourth order parabolic system. Semi-discretization in time and entropy estimates give the global existence and semiclassical limit of nonnegative weak solutions to the one-dimensional model with a nonnegative large initial value and a Dirichlet-Neumann boundary con-dition. Furthermore, the weak solutions are proven to exponentially approach constant steady state as time increases to infinity.
2008年04期 560-569页 [查看摘要][在线阅读][下载 185K] [下载次数：28 ] |[网刊下载次数：0 ] |[引用频次：1 ] |[阅读次数：0 ] - 王小龙;刘丽文;
This research examines how to use an option contract to coordinate a retailer-led supply chain where the market information can be updated. Based on Stackelberg game theory, we build a mode with one supplier and one retailer in which the retailer designs contracts to coordinate the supplier’s production in a two-mode production environment. This focuses on an option contract that consists of two option prices and one exercise price. By theoretical analysis and numerical example, we find that such a contract can coordi-nate the supplier and retailer to act in the best interest of the channel. The optimal pricing conditions are given as follows: First, option prices should be negatively correlated to the exercise price and should be in a relevant range. Second, the first-period option price should be no greater than the second-period price and should be linearly correlated to the second-period option price when the latter is beyond some threshold. The results show that such option contracts can arbitrarily allocate the extra system profit between the two parties so that each party is in a win-win situation.
2008年04期 570-580页 [查看摘要][在线阅读][下载 452K] [下载次数：190 ] |[网刊下载次数：0 ] |[引用频次：39 ] |[阅读次数：0 ] <正>Tsinghua Science and Technology (Tsinghua Sci Technol), a comprehensive academic journal sponsored by
2008年04期 581页 [查看摘要][在线阅读][下载 814K] [下载次数：8 ] |[网刊下载次数：0 ] |[引用频次：0 ] |[阅读次数：0 ]